Download Aptamers: Tools for Nanotherapy and Molecular Imaging by Rakesh N. Veedu PDF

By Rakesh N. Veedu

Aptamers, usually termed as ‘chemical antibodies,’ are an rising category of man-made ligands for effective target-specific molecular popularity. the target of this e-book is to focus on fresh advances and capability of aptamers in a variety of affliction stipulations. . This ebook makes a speciality of the purposes of aptamers in unique nanotherapy, detection, and in molecular imaging in a variety of sickness stipulations akin to melanoma, neurological illnesses and infectious diseases.

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Johansson, H. , Singer, B. , Uhlenbeck, O. , Zichi, D. , and Gold, L. (2000). , 28, p. E93. 16. , and Ikebukuro, K. (2012). Selection of DNA aptamers that recognize alpha-synuclein oligomers using a competitive screening method, Anal. , 84, pp. 5542–5547. 17. , Lagally, E. , Cheung, K. , and Haynes, C. A. (2014). A simple method for eliminating fixed-region interference of aptamer binding during SELEX, Biotechnol. , 111, pp. 2265–2279. 18. , and Klussmann, S. (2006). , 34, p. e86. 19. , Marth, J.

Advances in aptamer screening and small molecule aptasensors, Adv. Biochem. Eng. , 140, pp. 29– 67. 18. , Xing, J. , and Chen, J. (2014). Developing trends in aptamer-based biosensor devices and their applications, IEEE Trans. Biomed. , 8, pp. 4–14. 19. , and Ikebukuro, K. (2014). Emerging techniques employed in aptamer-based diagnostic tests, Expert Rev. Mol. , 14, pp. 143–151. 20. , Huang, P. , and Liu, J. (2014). Aptamer-based biosensors for biomedical diagnostics, Analyst, 139, pp. 2627–2640.

2013). Generation of high-affinity DNA aptamers using an expanded genetic alphabet, Nat. , 31, pp. 453–457. 43. , Bradley, K. , and Benner, S. A. (2014). In vitro selection with artificial expanded genetic information systems, Proc. Natl. Acad. Sci. U S A, 111, pp. 1449–1454. 44. , and Fan, C. (2010). Target-responsive structural switching for nucleic acid-based sensors, Acc. Chem. , 43, pp. 631–641. 45. , and Furste, J. P. (2012). Properties of an LNA-modified ricin RNA aptamer, Biochem. Biophys.

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Categories: Biomedical Engineering